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The term “synaptic plasticity” refers to the brain’s remarkable ability to change and adapt at the level of individual synapses—the junctions between neurons. What is synaptic plasticity? The term “synaptic plasticity” refers to the brain’s remarkable ability to change and adapt at the level of individual synapses—the junctions between neurons. These synaptic changes occur in response to variations in neural activity. Through repeated activation of specific neural circuits, brain training games strengthen synaptic connections associated with the targeted cognitive functions.